piromidic acid indications/contra

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 2209 19562-30-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • piromidic acid
  • pyromidic acid
Antibacterial against mainly gram negative organisms. It is used for urinary tract and intestinal infections.
  • Molecular weight: 288.31
  • Formula: C14H16N4O3
  • CLOGP: 0.63
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 1
  • TPSA: 86.63
  • ALOGS: -2.38
  • ROTB: 3

Drug dosage:

DoseUnitRoute
2 g O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC J01MB03 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Other quinolones
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000892 Anti-Infective Agents, Urinary
MeSH PA D012076 Renal Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.55 acidic
pKa2 6.43 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D01431 KEGG_DRUG
3I12WH4EWF UNII
3198 INN_ID
4855 PUBCHEM_CID
N0000167325 NDFRT
CHEMBL311350 ChEMBL_ID
CHEBI:32019 CHEBI
D010893 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None